Rabbit anti-XRN2 IHC Antibody Affinity Purified
Product Details
Specifications
The epitope recognized by IHC-00223 maps to a region between residue 900 and 950 human 5'-3' exoribonuclease 2 using the numbering given in entry NP_036387.2 (GeneID 22803).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4. Antibody was affinity purified using an epitope specific to XRN2 immobilized on solid support.
The epitope recognized by IHC-00223-T maps to a region between residue 900 and 950 of human 5'-3' exoribonuclease 2 using the numbering given in entry NP_036387.2 (GeneID 22803).
Immunoglobulin concentration was determined using Beer’s Law where 1mg/mL IgG has an A280 of 1.4.
Additional Product Information
XRN2 is a 5’-to-3’ exoribonuclease involved in 3’-end mRNA processing. XRN2 is important for transcription termination and is responsible for degrading the downstream 3’-end-cleaved RNA. Recent studies show that XRN2 is recruited to 3’-end processing machinery by p54nrb/PSF.
Alternate Names
5'-3' exoribonuclease 2; Dhm1-like protein; DHP protein
Applications
Epitope exposure is recommended.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
In some cases, the antibody may be diluted further than indicated.