Rabbit anti-Ymer Antibody Affinity Purified
Product Details
Specifications
Additional Product Information
Ymer was identified in a mass spectrometric study of epidermal growth factor signaling. It is a cytoplasmic tyrosine-phosphorylated protein that bears multiple ubiquitin-interacting domains. Recently Ymer has been implicated as a negative regulator of the NF-kappaB signaling pathway. Mutations in the gene that encodes Ymer, CCDC50, are the cause of autosomal dominant non-syndromic sensorineural deafness type 44.
Alternate Names
C3orf6; coiled-coil domain-containing protein 50; DFNA44; protein Ymer; YMER
Applications
All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.
Western blots of immunoprecipitates are performed using Goat anti-Rabbit Light Chain HRP Conjugate (Cat. No. A120-113P) with 5% Normal Pig Serum (Cat. No. S100-020) added to the blocking buffer.