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Goat anti-ApoA1 Polyclonal Antibody

bethyl
Bethyl Laboratories Catalog #
Target:
ApoA1
Reactivity:
Human
Host:
Goat
Clonality:
Polyclonal
Format:
Whole IgG
Isotype:
IgG
Purity:
Antiserum
100 ml

1 L

$400.00 $3,000.00
Qty:

Product Details

Specifications

Verified Reactivity
Human
Antigen Species
Human
Storage
2 - 8 °C
Shelf Life
2 years from date of receipt
Physical State
Liquid
Buffer
Serum containing 0.09% Sodium Azide
Request Formulation Change
Production Procedures
By immunoelectrophoresis, the antiserum reacts specifically with human Apo A1. This product meets European Union requirements for production of technical blood products.
Country of Origin
USA

Additional Product Information

Apo AI comprises approximately 70% of the protein moiety in HDL. It is a single polypeptide chain consisting of 243 amino acid residues without disulfide bound and with glutamic acid as the C-terminal residue and aspartic acid as the N-terminal residue. The molecular weight is reported to be 28 kDa (Brewer et al., 1978). The roles of Apo AI in HDL function include reverse cholesterol transportation, lipid cholesterol binding, lecithin-cholesterol acyl transferase (LCAT) activation, and receptor binding, which is responsible for cholesterol esterification in plasma. Besides participate in cholesterol metabolism, Apo AI and HDL also suppress neutrophil activation, inhibit bacterial endotoxin, induce trypanosomal lysis, and other physiological activities. (Brouillette et al., 2001). Apo AI levels may be inversely related to the risk of coronary disease. In previous research, Apo AI may affect diet-induced inflammation by either directly or indirectly altering lipid rafts. (Cheng et al., 2012)

335
APOA1
apolipoprotein A1
P02647
Apolipoprotein A-I

Alternate Names

apo(a); apo-AI; ApoA-I; Apolipoprotein A1; apolipoprotein A-I; epididymis secretory sperm binding protein