Rabbit anti-AATF/Che-1 Antibody Affinity Purified
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Catalog #
AATF/Che-1
Human
IP
,WB
Rabbit
Polyclonal
Whole IgG
Between 125 and 175
IgG
Unconjugated
Antigen Affinity Purified
Product Details
Human
Human
2 - 8 °C
1 year from date of receipt
AATF/Che-1 was identified as a protein that interacts with RNA polymerase II and is involved in the regulation of gene transcription and cell proliferation. AATF/Che-1 has been demonstrated to promote cell proliferation by acting as a competitor of histone deacetylase 1 (HDAC1) and interfering with HDAC1’s interaction with the growth inhibiting protein pRB. AATF has also been shown to function as a nuclear receptor coactivator and a repressor of apoptosis.
Alternate Names
Apoptosis-antagonizing transcription factor; BFR2; CHE1; CHE-1; DED; protein AATF; rb-binding protein Che-1
Applications