mTOR Pathway

Date of Publication: January 11, 2023

The mTOR pathway is triggered by nutrients, hormones such as insulin, and growth factors, resulting in cell growth and proliferation. The pathway is inhibited by hypoxia and nutrient deficiencies. Dysregulation or inhibition of this pathway is a characteristic of malignant cell proliferation, making the study and targeting of this cascade a critical target for cancer therapeutics.