Probe selection is one of the most important decisions made during the planning of a new lateral flow assay. The reporter particle choice impacts not only the achievable sensitivity, stability in the sample matrix, cost of the assay, and development time, but also determines whether a reader is required for the final signal readout.
This technical note compares the performance of passive conjugates prepared using BioReady™ 150 nm Citrate Gold Nanoshells and 40 nm Citrate Gold Nanospheres in Thyroid Stimulating Hormone (TSH) and SARS-Cov-2 Nucleocapsid Protein (SNP) lateral flow assay.